By Ernest Hodgson
A Textbook of contemporary Toxicology is a different source that gives either scholars and practitioners with a wide-ranging, obtainable assessment of the self-discipline. appropriate for classes in environmental, pharmacological, clinical, and veterinary toxicology, this crucial textual content positive aspects chapters written by way of specialists who tackle various key topics.The Fourth version comprises extra chapters on new techniques to toxicology - molecular equipment (-omics: toxicogenomics, proteomics, and metabolomics), bioinformatics, and platforms biology – and keeps the legacy of its predecessors to supply up to date insights into acute toxicity and chemical carcinogenesis, organ toxicity, in vitro and in vivo toxicity checking out, ecological chance evaluation, and plenty of different components of toxicology that support foster an outstanding comprehension of the field.Also featured within the Fourth variation are end-of-chapter questions and a suggestions handbook on hand individually for tutorial adopters.
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Additional info for A Textbook of Modern Toxicology, 4th Edition
Toxicology b. Poison c. Genomics d. Proteomics e. Metabolomics 2. Toxicity has been described as a cascade of events initiated by exposure to a harmful chemical. Name the principal steps in this cascade. 3. Name and define three important chemical use classes. CHAPTER 2 Introduction to Biochemical and Molecular Methods in Toxicology ERNEST HODGSON, GERALD A. LEBLANC, SHARON A. MEYER, and ROBERT C. 1 INTRODUCTION This chapter is not designed to summarize biochemical methods long used in toxicology such as colorimetric and radiometric methods for the investigation of xenobiotic metabolism, either in vivo or in vitro, but rather to give a brief summary of the methods of molecular, biochemical, and cellular biology that have become, more recently, of critical importance in toxicological research.
C. Smart and E. Hodgson. Hoboken, NJ: Wiley, 2008. , ed. A Textbook of Modern Toxicology, 3rd edition. Hoboken, NJ: Wiley, 2004. LeBlanc, G. A. Immunochemical techniques in toxicology. , eds. R. C. Smart and E. Hodgson. Hoboken, NJ: Wiley, 2008. Merrick, B. A. Proteomics. , eds. R. C. Smart and E. Hodgson. Hoboken, NJ: Wiley, 2008. Meyer, S. A. Cellular techniques in toxicology. , eds. R. C. Smart and E. Hodgson. Hoboken, NJ: Wiley, 2008. Oleksiac, M. F. Toxicogenomics. , eds. R. C. Smart and E.
They have increased our knowledge of the chemistry of poisons, the treatment of poisoning, the analysis of toxicants and toxicity, as well as modes of toxic action and detoxication processes, and specific molecular events in the poisoning process. With the publication of her controversial book, The Silent Spring, in 1962, Rachel Carson became an important influence in initiating the modern era of environmental toxicology. Her book emphasized stopping the widespread, indiscriminate use of pesticides and other chemicals and advocated use patterns based on sound ecology.
A Textbook of Modern Toxicology, 4th Edition by Ernest Hodgson