By Cindy Daoust
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Extra resources for Big Book of Patterns PreS-K
2002). Based on this supposition, an appreciable selective effect on LD may still remain. Another surprising aspect of this study was that a genome-wide sample of 47 simple sequence repeats (SSRs) demonstrated higher levels of LD than SNPs in candidate genes. The reason for the apparent difference between SNPs and SSRs is unclear at present, but it may reflect differences in the type of historical information captured by markers with different mutation rates (Remington et al. 2001). Thornsberry et al.
The quartet mutation in Arabidopsis where each of the products of meiosis develops as viable pollen grains thus representing an unordered tetrad, appears to offer a good avenue for gene conversion studies in plants. 6. A simplistic diagram showing the major difference between gene conversion and crossover. (A) Two DNA molecules. (B) Gene conversion after mismatch correction – the red DNA donates part of its genetic information (e–e' region) to the blue DNA. (C) DNA crossover – the two DNAs exchange part of their genetic information (f–f ' and F–F').
In small populations, the effects of genetic drift result in the consistent loss of rare allelic combinations. 8) where N is the effective population size and c is the recombination fraction between sites (Weir 1996). Selection (natural or artificial) at a locus is expected to reduce diversity and increase LD in the surrounding region (often colloquially termed “hitchhiking”). Also, selection for or against a phenotype controlled by alleles at two unlinked loci that show epistatic interaction may result in LD despite the fact that the loci are not physically linked.
Big Book of Patterns PreS-K by Cindy Daoust