By J. Cervós-Navarro, J. Artigas, B. J. Mršulja (auth.), Prof. Dr. Konstantin-Alexander Hossmann, Dr. Igor Klatzo (eds.)
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Extra resources for Cerebrovascular Transport Mechanisms: International Congress of Neuropathology, Vienna, September 5–10, 1982
34. 35. 36. 37. 38. 39. 40. 41. 32 Horton JC, Hedley-Whyte ET (1979) Protein movement across the bloodbrain barrier in hypervolemia. Brain Res 169:610-614 Landis DMD, Reese TS (1974) Arrays of particles in freeze-fractured astrocytic membranes. J Cell Biol 60:316-320 Lossinsky AS, Garcia JH, Iwanowski L, Lightfoote WE Jr (1979) New ultrastructural evidence for a protein transport system in endothelial cells of gerbil brains. Acta Neuropath (Berl) 47:105-110 Martinez-Palomo A, Erlig D (1975) Structure of tight junctions in epithelia with different permeability.
1. Light microscopic view of cat cerebral cortex incubated for AP activity; the reaction is very intense in the microvessels (arrows) and much weaker or absent in larger vessels (arrowheads). X 210 Fig. 2. Similar reaction for AP activity as shown in Fig. 1 observed under the electron microscope. ) is localized on the luminal plasmalemma of the Ee of the microvessel (arrows). In all electronmicrographs, L indicates the vessel lumen. X 29,000 the Ee suggests that in this area, extensive processes of dephosphorylation occur.
P. for 5'N is also present (arrowheads). X 75,000 Fig. 14. Reaction for AP in the white matter of the adjacent gyrus 24 hours after cold lesion. p. for AP appears solely on the abluminal side of the EC and in the basement membrane (arrowheads). X 22,000 Fig. 15. Microvessel from adjacent gyrus 7 days after cold injury. The reaction for AP is localized both in the luminal plasmalemma (arrows) and in the abluminal side of the EC (arrowheads). X 15,000 Summary Alkaline phosphatase (AP) is one of the enzymes which is highly active in the plasmalemma of endotheIial eelIs (ECs) of BBB-type microvessels.
Cerebrovascular Transport Mechanisms: International Congress of Neuropathology, Vienna, September 5–10, 1982 by J. Cervós-Navarro, J. Artigas, B. J. Mršulja (auth.), Prof. Dr. Konstantin-Alexander Hossmann, Dr. Igor Klatzo (eds.)