By Jenner, John; Thiermann, Horst; Worek, Franz
Regardless of ongoing efforts to ban the creation, garage and use of chemical war brokers fresh global occasions spotlight the long-lasting hazard to the inhabitants from those brokers. study efforts in a variety of international locations have led to novel insights into chemical war toxicology that has enabled the improvement of latest ways for the prognosis and remedy of chemical struggle poisoning. This publication offers an up to date treatise at the ongoing examine into the toxicology of chemical war brokers, the analysis and verification of publicity, and the pre- and post-exposure remedy of poisoning. Focussing at the basics of the toxicology of nerve brokers and vesicants, this publication will supply the reader a complete evaluate of the various various facets of chemical conflict agent toxicology. The textual content will entice toxicologists, biochemists and guns experts operating in and academia, and someone with an curiosity in chemical war toxicology or publicity
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Extra info for Chemical Warfare Toxicology, Volume 1
29, pp. 499–538. J. F. Mackworth and E. C. Webb, The inhibition of serum cholinesterase by alkyl fluorophosphonates, Biochem. , 1948, 42, 91–95. -E. Tammelin, Methyl-fluoro-phosphorylcholines. Two synthetic cholinergic drugs and their tertiary homologues, Acta Chem. , 1957, 11, 859–865. T. Fredriksson, Pharmacological properties of methylfluorophosphorylcholines. Two synthetic cholinergic drugs, Arch. Int. , 1957, 113, 101–113. J. Matousek and I. Masek, On the new potential supertoxic lethal organophosphorus chemical warfare agents with intermediate volatility, ASA Newsletter, 1994, 94–5, 1.
G. carbon tetrachloride and benzene. 1), also known as O mustard. T has somewhat greater vesicant activity than sulfur mustard, is less volatile and more persistent. Other nations mixed mustard with lewisite, which also accelerated the onset of effects and increased the vapour hazard. Medical treatment of mustard injuries causes major logistical problems, and military casualties may be unable to perform duties for weeks or permanently. It seems remarkable that there is still no effective treatment for mustard lesions other than symptomatic and palliative treatment.
Several other nations are suspected to have weaponised small quantities of BZ or an analogue. BZ had a number of disadvantages, particularly its slow onset and long duration of action, incapacitation in terms of the ability to conduct military operations was difficult to judge, and it was expensive to manufacture. 77 During the 1960s, potent opioids were the major focus of incapacitant research in several countries. An example is etorphine (M-99), a semi-synthetic hexacyclic opioid that is approximately 1000 times more potent than morphine and marketed for veterinary use as a knockdown agent for large game animals.
Chemical Warfare Toxicology, Volume 1 by Jenner, John; Thiermann, Horst; Worek, Franz